Author: dlende

The Rat Park

Here’s a great article on some of my favorite research, how creating a Rat Park (i.e., paradise for rats), leads to remarkably low rates of spontaneous drug use rates among animal models.  As the article goes, this research by Bruce Alexander “led him to conclude that drugs — even such hard drugs as heroin and cocaine — do not cause addiction; the user’s environment does.”  The Rat Trap piece over at The Walrus Magazine goes on to examine the Rat Park research, and then Alexander’s subsequent work on environmental causes for addiction.

One good quote: “Alexander’s research reveals that addiction rates are low when societies are stable, and they rise at times of social disruption. ‘The extreme case is the aboriginal people,’ he says. ‘You don’t have anything identifiable as addiction until you screw up their culture, and then alcoholism becomes a major problem. In extreme cases, addiction rates can go from zero to close to 100 percent.’  Such spikes suggest that environment is a stronger determinant of addiction than chemistry. As Alexander puts it, if you put a carton of eggs under a hydraulic press, it’s true some of the eggs will crack before others, but the problem isn’t the eggs. It’s the press.”

Still, understanding which eggs will crack, and why; and how and why specific cracks happen, and not other cracks, all provide an important role for more proximate research.  It is that mix, of environment through individuals down to mechanisms and then back out, which is particularly challenging but interesting in addiction.  And, in the end, that type of research might lead us to develop theoretical models that will go beyond treating either environments or genetics as hydraulic press models, imprinting us with their forms.  In any case, for getting started, it is crucial to recognize the context, the overall lay of the land, and Alexander’s work provides us one good (though not complete, for me at least) perspective on that.

The Family Dinner Deconstructed

National Public Radio had a radio broadcast yesterday morning on “The Family Dinner Deconstructed.”  Here’s the blurb: “The ritual of a family dinner has been praised as an antidote to bad grades and bad habits in kids. But as researchers look closer at the family dinner, they raise the question: Is it the mere act of eating together that counts, or is it that strong families are already more likely to have a family dinner?” 

The reporter does a wonderful job talking with a variety of researcher to focus in on the proximate features of the family dinner—conversations, relationships, rituals, emotions—and how they can impact physical and mental health.  For example, the quality of conversations at mealtime was a better predictor of reading development than parents actually reading to their children.  But what mattered was the content on dinner conservation, that it was complex and “rich with explanation, story telling, and more.”  Similarly, for physical and mental development (for example, eating disorders), specific behaviors at dinner proved important: roles assigned (setting the table, beginning and end to dinner); a genuine concern about daily activities; and a sense of empathy and concern for each other. 

While the radio cast pushes a double-blind study to “determine” the specific effects of a good-quality family dinner versus dinner-as-usual, the announcer rightly acknowledges that doing such research is a daunting prospect.  I would add that an ethnographic approach that builds on this educational and psychological research and that teases out the relationships between dinner, family interaction, and development as a joint physical-mental phenomenon could also add some great insights.

Sleep, Eat, Sex – Orexin Has Something to Say

Blogging on Peer-Reviewed ResearchOrexin is a neuropeptide which is released by the posterior lateral hypothalamus, and is linked to wakefulness and sleep, appetite regulation, and the motivation of sexual and addictive behaviors.  One apt way to think about it is as a hormone in the brain, combining some of the popularly conceived effects of adrenaline and testosterone into one. 

(Don’t get too excited now!  I am just trying to give you a way to think about it, that orexin works to promote arousal and response…)

I am writing a post on the links of orexin to appetitive behavior, particularly addiction, but I’ve generated a lot of material.  So I am going to give you this one first, which summarizes aspects of orexin (also known as hypocretin) and neurological function with respect to sleep, appetite and sex. 
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Denial

Today I will lecture to my students in my Alcohol and Drugs class on denial.  We had a provocative discussion of the topic last Thursday, building off our reading of the wonderful and powerful memoir Drinking: A Love Story by Caroline Knapp. 

A group of students opened last Thursday’s class with a presentation that framed denial in the two ways it is generally discussed in addiction (in the US).  As I wrote to this group to help in preparing their presentation, “There is a basic debate in the addictions field (particularly alcoholism) on the role and importance of denial in addiction and recovery.  On the one side, denial is seen as a defining feature of addiction and breaking through denial as a core component of successful recovery.  On the other side, denial is seen as a marginal feature of addiction, likely the result of some other internal problem or even of social relations.  In this approach, attacking denial can backfire, causing anger in the substance abuser while not addressing either addiction itself or the promotion of therapeutic change.” 

After the students gave their presentation, I wanted to encourage class discussion, and used a technique I often employ, getting them to reflect on their own everyday lives and what that can tell us about ourselves.  I asked the class to write down an example of someone they knew “in denial,” and then give their gut reaction about why they think that person reacted that way.  In other words, I wanted some ethnographic data and some culturally-framed “explanations” to generate discussion.  It worked. 
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Neuroscience On Out: The Forest and the Trees

Often on this blog we have argued about the relevance of neuroscience to our work as anthropologists.  Today, however, I want to turn the tables.  Neuroscience needs anthropology.  Given the emerging models of neural function, with their emphasis on embodied learning and active interaction with the environment, some of neuroscience’s best ideas can only be tested in the field. 

This thought came to me through my colleague Cameron Hay, an anthropologist at Miami University in Ohio.  I was reading over a near-complete draft of her paper on memory, anxiety and healing among the Sasak in Indonesia.  Cameron wrote: 

“Neuroscientists are well aware that the isolated models of mind and its cognitive processes that they tend to study are invalid and that the person’s social, cultural, and physical environment has ‘an active role in driving cognitive processes’ (Henningsen and Kirmayer 2000: 472-3). Neuroscientific methods do not allow for the kind of holistic exploration that anthropology encourages, therefore, the link between anxiety and memory retrieval is somewhat under explored; however, there are some tantalizing associations.”

 While laboratory research and even ecologically-valid experimentation certainly have a vital role in expanding our current understanding of our brains, the extension from brain research to the workings of the mind and behavior is not a simple step.  Extrapolation is, in effect, bad science, because it is not based on scholarly research. 
Continue reading “Neuroscience On Out: The Forest and the Trees”