I have been wanting to write a post about the placebo effect for some time, after finding a wonderful YouTube video about getting drunk without being drunk. And then today I saw a very different “placebo effect” that also drives home Dan Moerman’s point when he says that the placebo effect is better thought of as “the meaning response.” (Moerman is an anthropologist, of course.)
The video, How to Get Drunk Without Drinking, shows Derren Brown demonstrating “a method I used at university which allows people to recreate any drug state, adrenaline, alcohol, you name it, without actually taking the drug.” (If it doesn’t play, you can go directly to the YouTube version.) What is so striking about the video is Brown’s use of imagination, embodiment, practice, suggestion, and memory to accomplish the effect, and the ability of the brain to then switch between such different states so quickly. It’s also quite funny!
The other piece, The Cure by Sarah Manguso, is adapted from her forthcoming memoir The Two Kinds of Decay. Manguso writes of being twenty-one, her life in danger from an auto-immune disease, and her desire to make love to someone. Her own antibodies were attacking her body, as she wryly notes, “trying to destroy my nervous system — a misperception that caused me a lot of trouble.” She returned to college with a huge tube sticking out of her chest, a necessary part of the regular blood treatments she needed.
“My blood was removed and cleaned and put back more than 50 times. After that, my hematologist tried another treatment: massive gamma-globulin infusions. The second infusion kept me going for three months, and it was decided I wouldn’t have to have my plasma replaced again. My neurologist said I’d turned a corner, so after 11 1/2 months, my central line was pulled.”
“I believed, though, that I would stop secreting antibodies only after I had sexual intercourse. And though I looked worse than I ever had in my life, thanks to the steroids — I was fat and swollen, covered in acne, and had a gruesomely round face — I thought my legendarily promiscuous musician friend might still be interested.”